Adrenoleukodystrophy (ALD) is a hereditary congenital disorder, involving degradation of the white matter in the brains (leukodystrophy) both in children and adults. Moreover, the most common peroxisomal disorder. In peroxisomal disorders, there is a change in the genetic material a disorder in the peroxisomes . Peroxisomes are small organs (organelles) in a cell, using enzymes – enzymes-guiding chemical reactions. ensure the degradation of waste. This disease affects the degradation of waste disturbed, so they accumulate in the cells. The accumulation of waste is toxic and difficult operation of the cells. This finally causes damage to organs and tissues.
ALD is characterized by a progressive degradation of insulation of the nerves in the central nervous system (brains and spinal cord) that is associated with insufficient functioning of the adrenal glands. This causes various symptoms, including paralysis and impaired motor control (ataxia). (more…)
